许杰华,男,陕西榆林人,医学博士,副教授,硕士研究生导师。

本科毕业于原西安医科大学临床医学系。研究生就读西安交通大学,2003年获人体解剖学与组织胚胎学硕士学位,2007年获人体解剖学与组织胚胎学博士学位。2006.7-2007.7期间在新加坡国家神经研究所癫痫病研究室进行合作研究。一直从事癫痫、神经发育、高等医学教育研究及解剖学教学工作。在国内、外期刊已发表论文30余篇。

主持国家自然科学基金、陕西省社发攻关项目、西安交通大学光华基金等研究项目。熟悉癫痫动物模型制备、动物行为学、神经追踪、蛋白定量、实时定量PCR等研究方法。

研究方向:1)癫痫的发病机制及防治;2)神经发育调控机制;3)高等医学教育模式研究。

代表性研究论文:

1.Xu JH,Tang FR (2018 Sep 12) Voltage-Dependent Calcium Channels, Calcium Binding Proteins, and Their Interaction in the Pathological Process of Epilepsy. International journal of molecular sciences 19(9).

2.Xu JH,Wang H, Zhang W, Tang FR (2018) Alterations of L-type voltage dependent calcium channel alpha 1 subunit in the hippocampal CA3 region during and after pilocarpine-induced epilepsy. Neurochemistry international 114:108-119

3.Xu JH,Yang ZB, Wang H, Tang FR. Co-localization of L-type voltage dependent calcium channel alpha 1D subunit (Ca(v)1.3) and calbindin (CB) in the mouse central nervous system.Neurosci Lett.2014. 561:80-5.

4.Xu JH,Long L, Wang J, Tang YC, Hu HT, Soong TW, Tang FR. Nuclear Localization of Ca(v)2.2 and its Distribution in the Mouse Central Nervous System, and Changes in the Hippocampus during and after Pilocarpine-induced Status Epilepticus. Neuropathol Appl Neurobiol. 2010, 36(1): 71-85.

5.Xu JH,Long L, Tang YC, Zhang JT, Hu HT, Tang FR. CCR3, CCR2A and MIP-1α, MCP-1 in the mouse Hippocampus during and after Pilocarpine Induced Status Epilepticus. Neuropathol Appl Neurobiol. 2009, 35(5): 496-514.

6.Xu JH, Long L, Tang YC, Hu HT, Tang FR.Cav1.2, Cav1.3 and Cav2.1 in the mouse hippocampus during and after pilocarpine induced status epilepticus. Hippocampus, 2007, 17(3): 235-251.