梁玲利，博士，教授，博士/硕士生导师。基础医学院青年学术委员会副主任委员，中国神经科学学会感觉和运动分会委员，中国神经科学学会神经内稳态和内分泌分会委员，中国生理学会疼痛转化研究专业委员会，中国药物滥用防治协会成瘾与脑科学分会委员，陕西省生理科学会理事。

Lingli Liang, Ph.D., Professor in the Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center. Deputy Chairman of the Youth Academic Committee of Basic Medical College, Member of the Sensory and Motor Branch of the Chinese Neuroscience Society, member of the Neurohomeostasis and Endocrinology Branch of the Chinese Neuroscience Society, member of the Pain Transformation Research Committee of the Chinese Physiological Society, member of the Addiction and Brain Science branch of the Chinese Association of Drug Abuse Prevention and Treatment, and member of the Shaanxi Physiological Science Society.

Contact information:

E-mail: ll2017@xjtu.edu.cn

Personal homepage：http://gr.xjtu.edu.cn/web/ll2017/home

Researchgate：https://www.researchgate.net/profile/Lingli_Liang

Addresses：

1. Science and Education Building 807, Yanta Campus, Xi'an Jiaotong University

西安交通大学雁塔校区科教楼807

2. Hongren Building 4024, Western China Science & Technology Innovation Harbour

中国西部创新港21号泓仁楼4024室

研究领域（方向）：

慢性疼痛的分子机制

Research interest: Molecular mechanisms of chronic pain.

教育经历：

1997-2002：郑州大学预防医学专业（B.A.）

2002-2005：上海中医药大学基础医学院中西医结合基础生物专业（M.S.）

2006-2010：复旦大学神经生物学研究所脑科学研究院神经生物学专业（Ph.D.）

Educations:

1997-2002: Bachelor Degree in Preventive Medicine/General Medicine from Zhengzhou University；

2002-2005: Master Degree in Cooperation of Chinese and Western medicine (Biology) from Shanghai University of Traditional Chinese Medicine；

2006-2010: PhD Degree in Neurobiology from Fudan University;

工作经历：

2023.1-至今：西安交通大学，教授/博士生导师

2017.9-2022.12：西安交通大学，副教授/博士生导师

2013.7-2017.8：美国新泽西罗格斯大学，Research associate

2010.6-2013.6：在美国约翰霍普金斯大学，博士后

2005.9-2006.9：上海中医药大学，助教

Jobs:

2010.6-2013.6: Postdoctoral researcher at Johns Hopkins University

2013.7-2017.8: Research associate in New Jersey Medical School, Rutgers University

2017.9-2022.12: Associate Professor in Xi’an Jiaotong University

2023.1-present: Professor in Xi’an Jiaotong University

主要科研项目：

近年主持的科研项目：

1.国家自然科学基金（面上项目，项目号82271253）

2.国家自然科学基金（面上项目，项目号31871065）

3.国家自然科学基金（青年项目，项目号81701112）

4.陕西省自然科学基础研究计划一般项目（面上，2019JM-128，）

5.中国博士后科学基金第63批面上资助（项目号：2018M633527）

6.陕西省博士后项目资助（项目号：2018BSHEDZZ147）

7.西安交通大学基本科研业务费自由探索（sxzy012019144）

8.西安交通大学“新教师科研支持计划”

Grants and fundings:

1. 2023.1-2026.12, National Natural Science Foundation of China (82271253)

2. 2019.1-2022.12, National Natural Science Foundation of China (31871065)

3. 2018.1-2020.12, National Natural Science Foundation of China (81701112)

4. 2019.1.1-2020.12.31, Natural Science Foundation of Shaanxi Province (2019JM-128)

5. 2018.7.1-2020.6.30, China Postdoctoral Science Foundation (2018M633527)

6. 2018.7.1-2020.6.30, Postdoctoral Science Foundation of Shaanxi Province (2018BSHEDZZ147)

7. 2017.9.1-2020.12.31, Basic Science Foundation from Xi’an Jiaotong University

8. 2019.1.1-2021.12.31, Basic Science Foundation from Xi’an Jiaotong University (sxzy012019144)

学术及科研成果、专利、论文：

在国内外杂志发表论文40余篇，包括国际著名期刊Nature communication、Neuron、Journal of Pain、Anesthesiology等。

More than 40 publications in domestic and foreign journals including Nature communication, Pain, Anesthesiology and other international journals.

Major publications in recent 5 years:

  1. Xuan Zhu*, Siyi Liu, Lixia Tian, Xiang Li, Rongrong Yao, Yunhan Zhao, Zihao Gao, Xue-Ru Liu, Xin-Qi Liu, Fu-Quan Huo, Lingli Liang#. Spinal interleukin-16 mediates inflammatory pain via promoting glial activation. Int Immunopharmacol. 2024 Jan 25;127:111411. IF: 5.60.

  2. Siyi Liu*, Shuting Yang, Xuan Zhu, Xiang Li, Xi Zhang, Xiaoqiong Zhou, Hong Cheng, Fu-Quan Huo, Qingxiang Mao#, Lingli Liang#. Spinal apolipoprotein E is involved in inflammatory pain via regulating lipid metabolism and glial activation in the spinal dorsal horn. Biol Direct. 2023 Dec 9;18(1):85. IF: 5.50.

  3. Siyi Liu*, Shuting Yang, Xiaoqiong Zhou, Xuan Zhu, Linping Xu, Xiang Li, Zihao Gao, Tingkai Sun, Jianxiong Wei, Lixia Tian, Hong Cheng, Guihua Wei, Fu-Quan Huo, Lingli Liang#. Nerve injury-induced upregulation of apolipoprotein E in dorsal root ganglion participates in neuropathic pain in male mice. Neuropharmacology. 2023 Feb 15;224:109372. IF: 4.70.

  4. Xiaoqiong Zhou*, Jianxiong Wei, Hong Cheng, Lixia Tian, Xuan Zhu, Yidan Zhang, Linping Xu, Guihua Wei, Fu-Quan Huo, Lingli Liang#. CoREST1 in primary sensory neurons regulates neuropathic pain in male mice. Life Sci. 2023 Nov 1;332:122088. IF: 6.10.

  5. Jianxiong Wei*, Shuyang Chang*, Siyi Liu, Lixia Tian, Xuan Zhu, Shuo Wang, Xiaoqiong Zhou, Yuying Wang, Linping Xu, Fu-Quan Huo, Lingli Liang#. Lysine-specific demethylase 1 in primary sensory neurons participates in chronic compression of dorsal root ganglion-induced neuropathic pain. Brain Res Bull. 2022 Dec;191:30-39. IF: 3.80.

  6. Qingxiang Mao*, Lixia Tian, Jianxiong Wei, Xiaoqiong Zhou, Hong Cheng, Xuan Zhu, Xiang Li, Zihao Gao, Xi Zhang, Lingli Liang#. Transcriptome analysis of microRNAs, circRNAs, and mRNAs in the dorsal root ganglia of paclitaxel-induced mice with neuropathic pain. Front Mol Neurosci. 2022 Aug 31;15:990260. IF: 4.80.

  7. Siqi Wei*, Shuyang Chang, Yue Dong, Linping Xu, Xiaocui Yuan, Hong Jia, Jun Zhang#, Lingli Liang#. Electro-acupuncture suppresses AXL expression in dorsal root ganglion neurons and enhances analgesic effect of AXL inhibitor in spinal nerve ligation induced-neuropathic pain rats. Neurochem Res. 2021; 46(3):504-512. IF: 3.996.

  8. Lingli Liang*#, Jun Zhang#, Lixia Tian, Shuo Wang, Linping Xu, Yingxuan Wang, Qingying Guo-Shuai, Yue Dong, Yu Chen, Hong Jia, Xuewei Yang, Chunmei Yuan. AXL signaling in primary sensory neurons contributes to chronic compression of dorsal root ganglion-induced neuropathic pain in rats. Mol Pain. 2020; 16:1744806919900814. IF: 3.395.

  9. Shuo Wang*, Siyi Liu*, Linping Xu*, Xuan Zhu, Wanyuan Liu, Lixia Tian, Yu Chen, Yuying Wang, Borra. V. Padma Nagendra, Shushan Jia, Lingli Liang#, Fu-Quan Huo#. The upregulation of EGFR in the dorsal root ganglion contributes to chronic compression of dorsal root ganglions-induced neuropathic pain in rats. Mol Pain. 2019; 15:1744806919857297. IF: 3.395.

  10. Lixia Tian*, Yu Chen, Shuyang Chang, Linping Xu, Xiaoqiong Zhou, Qingxiang Mao, Lingli Liang#. Antisense oligonucleotides targeting alternative splicing of Nrcam exon 10 suppress neurite outgrowth of ganglion sensory neurons in vitro. Neuroreport. 2021; 32(7):548-554. IF: 1.837.

  11. Lingli Liang*, Shaogen Wu, Corinna Lin, Yun-Juan Chang, Yuan-Xiang Tao#. Alternative splicing of Nrcam gene in dorsal root ganglion contributes to neuropathic pain. J Pain. 2020; 21(7-8):892-904. IF: 5.820.

  12. Lingli Liang*#, Jianxiong Wei, Lixia Tian, Borra V Padma Nagendra, Feng Gao, Jun Zhang, Linping Xu, Haoruo Wang, Fu-Quan Huo. Paclitaxel Induces Sex-biased Behavioral Deficits and Changes in Gene Expression in Mouse Prefrontal Cortex. Neuroscience. 2020; 426:168-178. IF: 3.590.

  13. Lingli Liang*, Jian-Yuan Zhao, Ticehurst Kathryn, Alex Bekker, Yuan-Xiang Tao. BIX01294, a G9a inhibitor, alleviates nerve injury-induced pain hypersensitivities during both development and maintenance periods. Transl Perioper Pain Med. 2019; 6(4): 106–114.